Correlation of Time to Treatment with Attack Duration in the Sebetralstat KONFIDENT Phase 3 Trial

Craig TJ, Bernstein JA, Longhurst H, Hao J, Smith MD, Audhya PK, Yea CM, Maurer M

On-demand Treatment of Laryngeal Hereditary Angioedema Attacks with Sebetralstat: Pooled Analysis from KONFIDENT and KONFIDENT-S

Aygören-Pürsün E, Bernstein JA, Lumry WR, Audhya PK, Hao J, Smith MD, Yea CM, Riedl MA

Indirect treatment comparison of oral sebetralstat and intravenous rhC1-INH as on-demand treatments for hereditary angioedema

Li HH, Mager M, Craig TJ, Manning ME, Hummel N, Wang A, Audhya PK, Bernstein JA

Phase 3 KONFIDENT Trial of Oral Sebetralstat for Treatment of Hereditary Angioedema Attacks: Analysis of the European and US Patient Subgroups

Zanichelli A, Aygören-Pürsün E, Bernstein JA, Farkas H, Lumry WR, Maurer M, Riedl MA, Hao J, Smith MD, Audhya PK, Yea C, Cohn DM

ACARE Global Angioedema Forum 2024 (GAF)

Impact of Oral Sebetralstat on Anxiety Associated with Hereditary Angioedema Attacks in the Phase 3 KONFIDENT Trial

Maurer M, Cohn DM, Bernstein JA, Farkas H, Lumry WR, Riedl MA, Zanichelli A, Hao J, Smith MD, PK Audhya, Yea CM, Aygören-Pürsün E

ACARE Global Angioedema Forum 2024 (GAF)

Pooled Sebetralstat Placebo-controlled Safety for On-demand Treatment of Hereditary Angioedema (Oral Presentation)

Aygören-Pürsün E

Bradykinin Symposium 2024

Pooled Sebetralstat Placebo-controlled Efficacy for On-demand Treatment of Hereditary Angioedema (Poster Presentation)

Aygören-Pürsün E

Bradykinin Symposium 2024

Oral Sebetralstat for On-Demand Treatment of Hereditary Angioedema Attacks

Riedl MA, Farkas H, Aygören-Pürsün E, Psarros F, Soteres DF, M.D., Staevska M, Cancian M
New England Journal of Medicine

Sebetralstat: A Rapidly Acting Oral Plasma Kallikrein Inhibitor for the On-Demand Treatment of Hereditary Angioedema

Feener EP, Davie RL, Murugesan N, Pethen SJ, Hampton SL, Smith MD, Audhya PK, Yea CM

Drugs and Drug Candidates

Evaluation of patient‐reported outcome measures for on‐demand treatment of hereditary angioedema attacks and design of KONFIDENT, a phase 3 trial of sebetralstat

Cohn DM, Aygören-Pürsün E, Bernstein JA, Farkas H, Lumry WR, Maurer M, Zanichelli A, Iverson M, Hao J, Smith MD, Yea CM, Audhya PK, Riedl MA

Clinical Translation Allergy